Diet and Amyotrophic Lateral Sclerosis (ALS)

these data on BM a a neurotoxin concentrations and animals in South Florida waters indicate that the situation in Guam is not unique it looks like BM a it could be found in high concentrations in aquatic animals in many areas of the world this could explain ALS clustering around lakes in New Hampshire up to 25 times the expected rate of ALS with some families eating fish several times a week or in Wisconsin where the most significant ALS risk factor was the past consumption of fish out of Lake Michigan or clustering in Finland’s Lakeland district or maybe seafood eaters in France around the Baltic Sea building up particularly in fish mussels and oysters when I think algae blooms I think the Chesapeake Bay near where I live that gets choked off thanks in part to the poultry industry pollution and indeed there was a recent report linking BMAA exposure to ALS in Maryland ALS victims living within a half mile of each other raised some eyebrows at the Hopkins als Center the victim zj2 chesapeake blue bay blue crabs every week and so they tested a few and two out of three crabs tested positive for BMAA indicating that the neurotoxin is present in the aquatic food chain of the Chesapeake Bay and the potential route for human exposure to bring the story full circle things in Guam are looking up the ALS epidemic there may have been triggered by their acquisition of guns but now the epidemic appears to be over thanks to the near extinction of fruit bats due to overhunting but while the rates decline in Guam neurodegenerative disease like ALS around the rest of the world are on the rise it’s plausible that humans have been exposed to some level of BMAA through our evolutionary history but the increase in algae blooms as a result of human activities is probably increasing this exposure there’s a general consensus that harmful algal algal bloom are increasing worldwide thanks in part to industrialize agriculture more people means more sewage fertilizer manure which may mean more algae which may mean more exposure to this neurotoxin leading to a possible increased incidence of neurodegenerative diseases such as Alzheimer’s Parkinson’s and ALS BMAA is a strong contender as the cause of our least a major contributor to the cause of both endemic and sporadic ALS and Alzheimer’s disease and possibly conferring risk for Parkinson’s disease as well the ramifications of this discovery are enormous with substantial and ever-growing evidence at BMAA does play a role in the onset and progression of neurodegenerative diseases the most important question is what mode of activity does BMAA exert what no it’s not the most important question is how do we reduce our risk we know that the presence of BMAA and aquatic food chains could be a significant human health hazard there may even be a synergistic toxicity between mercury and BMA making certain fish even riskier until more is known about the possible link of BMAA to Alzheimer’s and ALS may be prudent to limit exposure of BMAA in the human diet you

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